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Tachedjian et al. This unexpected finding provides insight into the actions of the inhibitors and into the dimerization process, neither of which is well understood. Therapies involving three-drug combinations are now the standard treatment for HIV-1 infections. Despite the successes with such treatments, there are still considerable problems with drug toxicity and the development of viral resistance. The approved drugs inhibit two viral enzymes: reverse transcriptase RT and protease. All of the protease inhibitors are substrate analogs; however, there are two types of RT inhibitors, nucleoside analogs and nonnucleoside inhibitors NNRTIs.

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I felt a similar empathy when I switched on “Indian Matchmaking,” Netflix’s new, controversial docu-series that follows Sima Taparia, a nosy Journalism for every part of life. Schools Reopening: The State of Play for K

How has it been for you since the show premiered? It hit me yesterday that, a week ago, no one in the world knew my name except for my friends and my family. I watched [the series] at 2 a. Why did you decide to do the show? Are you looking for your significant other? I thought it was spam. They wanted to Skype, and then the process kicked off with the casting team. I thought it might work. Why not?

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Indian Matchmaking: The ‘cringe-worthy’ Netflix show that is a huge hit

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Molecular matchmaking: NNRTIs can enhance the dimerization of HIV type 1 reverse transcriptase

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